Aetna Testosterone Cypionate Injection Depo-Testosterone

Testosterone use and male infertility patient education fact sheet

Only two patients discontinued therapy for skin related issues. The most common adverse event is pellet extrusion, with an incidence of 10% (21). Other adverse events include site infections, bleeding, and fibrosis at the insertion site (12). Potential advantages of pellet usage include the infrequency of dosing, guaranteed compliance, and lack of transference. However, administration is invasive requiring skin incision and local anesthesia. There are also concerns regarding pellet removal for patients experiencing androgen related side effects.

Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration. The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. Testosterone cypionate injection, USP, for intramuscular injection, contains testosterone cypionate which is the oil-soluble 17 (beta)-cyclopentylpropionate ester of the androgenic hormone testosterone. Studies have found both an increase and decrease in high-density lipoprotein cholesterol. An increase was found to occur after 3 months increasing further during 12 months (43), after 6 months, (35) or close to 1 year (44). Below is a list of medications that can interact with testosterone cypionate.

However, it is important to note that this therapy does not treat the underlying cause of the low testosterone. This article will use the terms “male,” “female,” or both to refer to sex assigned at birth. Keep your medication in a safe place to protect it from theft. Selling or giving away this medication is dangerous and against the law. This depends on your dose and is something you’ll discuss with your clinician and clinical team in training.

The PK profile of TU does not demonstrate supratherapeutic peaks, and trough levels are seen later after each injection when compared to TE and TC (47). Overall, there was a significantly lower number of skin irritation events in the gel groups compared to the patch group. Only six of 205 subjects in the gel groups discontinued therapy; two were related to drug specific adverse effects (hypertension and mood swings). The study concluded that Vogelxo® gel is better tolerated than transdermal testosterone patches, and can better normalize serum testosterone levels with titration (36).

Testosterone cypionate is a generic prescription testosterone injection for men with low testosterone levels. Low testosterone can you have pcos with normal testosterone levels be due to problems with the testicles, called primary hypogonadism, or problems with hormones that stimulate testosterone production. Healthcare professionals also use testosterone cypionate injections off-label for transgender hormone therapy or delayed puberty.

This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. If you think you’ve used too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away. Testosterone cypionate is available as the brand-name drug Depo-Testosterone. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Levels of circulating testosterone peak within 10 to 12 hours of initial administration, and reach steady state within 24 hours (14). When the product is discontinued, testosterone levels drop below normal within two to 4 hours, allowing for quick reversal if necessary. The preparation mimics physiological circadian testosterone rhythm, with serum levels quickly increasing after insertion and peak levels obtained by the second dose with no accumulation over time (15).

With the guidance of a qualified healthcare provider, you can develop a personalized protocol that supports your hormone optimization goals safely and effectively. Testosterone Cypionate is also popular in performance enhancement due to its anabolic effects. It increases protein synthesis and nitrogen retention, both vital for building muscle tissue.

Please speak with your doctor about what you should do if you experience these or other side effects. Ask your doctor, nurse or pharmacist how to safely discard unused medicines, needles and syringes. If you have a painful erection or an erection for more than 4 hours, seek medical care right away.

Testosterone Cypionate Injection USP is no longer being manufactured for sale in Canada. For brands that may still be available, search under testosterone cypionate. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.